Effects
246Browse health outcomes and the interventions that produce them.
- health adverse
Headache
Painful sensations in the head of various types (pressure, throbbing, bursting), intensity, and location, occurring as a side effect.
438 interventions · 0 stacks
- health adverse
Nausea
An unpleasant sensation in the epigastric region and throat, often preceding vomiting. One of the most common side effects of many supplements, especially when taken on an empty stomach or in high doses.
366 interventions · 0 stacks
- psyche
Mood Improvement
Top: Bromantane · Caffeine · CBD
316 interventions · 22 stacks
- health adverse
Digestive Discomfort
A general term covering various unpleasant sensations in the gastrointestinal tract: heaviness, abdominal pain or cramps, heartburn, nausea, belching, flatulence, not associated with a specific diagnosis.
285 interventions · 0 stacks
- mind adverse
Dizziness
Feeling of instability, rotation of surrounding objects or one's own body, 'lightheadedness', impaired balance. May be accompanied by nausea.
278 interventions · 0 stacks
- psyche
Anxiety Reduction
Top: 5-HTP · Amanita Pantherina · Aniracetam
262 interventions · 22 stacks
- psyche adverse
Insomnia
Sleep disturbance manifested by difficulty falling asleep, frequent nighttime or early morning awakenings, feeling of non-restorative sleep. Often associated with the stimulating effect of the supplement.
257 interventions · 0 stacks
- psyche adverse
Increased Anxiety
Occurrence or intensification of feelings of restlessness, nervousness, tension, fear, or panic attacks during supplement intake.
252 interventions · 0 stacks
- psyche
Fatigue Reduction
Top: Shilajit · Astragalus · Bhastrika Pranayama
245 interventions · 22 stacks
- health adverse
Diarrhea
Frequent (more than 3 times a day) loose or unformed stools, often caused by increased intestinal motility, impaired water absorption, or the irritating effect of the supplement. Can lead to dehydration.
213 interventions · 0 stacks
- mind
Concentration Improvement
Top: Alternate Nostril Breathing · Animal Flow · Bhastrika Pranayama
211 interventions · 21 stacks
- psyche
Sleep Quality Improvement
Top: 5-HTP · Amanita Pantherina · Chamomile
208 interventions · 22 stacks
- health
Inflammation Reduction
Top: Acupuncture · Face Icing / Cryo Rollers · TB-500 (Thymosin Beta-4 Acetate)
207 interventions · 19 stacks
- psyche
Stress Resilience Improvement
Top: CBD · Contact Improvisation · Cycle Syncing
202 interventions · 22 stacks
- mind adverse
Drowsiness
Increased tendency to sleep during the daytime, feeling of lethargy, decreased attention and reaction speed. Can interfere with daily activities and be dangerous when driving.
191 interventions · 0 stacks
- mind
Brain Fog Reduction
Top: Adrafinil · Bhastrika Pranayama · Caffeine
182 interventions · 22 stacks
- health
Cardiovascular System Support
Top: Cinnamon Extract · Acetyl-L-Carnitine (ALCAR) · Acupuncture
180 interventions · 21 stacks
- psyche adverse
Physical Fatigue
A feeling of bodily exhaustion, lack of energy, muscle weakness, and weariness that is not justified by preceding physical activity. Occurs as an undesirable side effect.
176 interventions · 0 stacks
- psyche adverse
Irritability
Increased excitability, tendency towards negative emotional reactions (anger, dissatisfaction) to minor stimuli, reduced tolerance. Can interfere with social interaction.
169 interventions · 0 stacks
- health
Antioxidant Protection Enhancement
Top: Cinnamon Extract · Lutein · Alternate Day Fasting
156 interventions · 21 stacks
- health
Immune System Support
Top: Chaga · Garlic · Spend Time in Nature
155 interventions · 21 stacks
- health
Neuroprotective Effect
Top: Ergothioneine · Fasting Mimicking Diet · Fisetin
154 interventions · 22 stacks
- psyche adverse
Mental Fatigue
Feeling of exhaustion of mental resources, difficulty concentrating, remembering, making decisions, decreased mental clarity, occurring as an undesirable effect.
152 interventions · 0 stacks
- body adverse
Muscle Tension
Feeling of stiffness, 'tightness', increased tone in muscles, often in the neck, shoulders, back.
147 interventions · 0 stacks
- health adverse
Allergic Reaction
Inappropriate immune system response to a supplement component, manifesting in various symptoms: skin rash (hives), itching, swelling (including angioedema), runny nose, tearing, cough, difficulty breathing, anaphylaxis.
143 interventions · 0 stacks
- mind
Memory Improvement
Top: Aniracetam · Cerebrolysin · Coluracetam
137 interventions · 19 stacks
- health adverse
Abdominal Bloating
Feeling of fullness and distension in the abdomen due to excessive gas accumulation in the intestines, often accompanied by discomfort, rumbling, belching, or flatulence.
135 interventions · 0 stacks
- body adverse
Muscle Ache (Myalgia)
Aching, dull, or sharp pain in muscles, not related to physical exertion or injury.
135 interventions · 0 stacks
- mind adverse
Brain Fog
Subjective feeling of reduced mental clarity, difficulty concentrating, formulating thoughts, slowed cognitive processes. Described as 'cotton wool' or 'fog' in the head.
134 interventions · 0 stacks
- body
Blood Flow Improvement
Top: Bhastrika Pranayama · Contrast Limb Baths · Deep Tissue Massage
131 interventions · 20 stacks
- mind
Improving neuroplasticity
Top: Fasting Mimicking Diet · NSI-189 · Fasoracetam
129 interventions · 20 stacks
- body adverse
Skin Rash / Irritation
Appearance of various undesirable skin reactions: redness, itching, eruptions (spots, papules, blisters), peeling, dryness, not related to allergy.
127 interventions · 0 stacks
- health adverse
Pain
Occurrence or intensification of unpleasant sensory and emotional experiences associated with actual or potential tissue damage, as an undesirable effect of taking a supplement. Can manifest in various forms and locations (e.g., headache, muscle pain, joint pain, abdominal pain).
125 interventions · 0 stacks
- psyche adverse
Mood Swings
Rapid, abrupt, and often unmotivated changes in emotional state, from euphoria or irritability to depression or tearfulness. May be related to effects on neurotransmitters or hormonal balance.
122 interventions · 0 stacks
- health
Analgesic Effect
Top: Boswellia · Chymotrypsin · Cissus Quadrangularis
117 interventions · 17 stacks
- health adverse
Increased Injury Risk
Increase in the likelihood of sustaining physical injuries (sprains, ligament tears, fractures, falls) during supplement intake or practice. May be associated with decreased coordination, dizziness, altered perception, excessive risk-taking behavior under the influence of stimulants, masking of pain allowing overexertion, or weakening of connective tissue.
116 interventions · 0 stacks
- psyche adverse
Nervousness and Restlessness
Feeling of inner tension, anxiety, 'internal tremor', inability to sit still, need to constantly move. Often associated with taking CNS stimulants.
114 interventions · 0 stacks
- mind
Increase Self-Awareness
Top: Continuous Glucose Monitoring · Kripalu Yoga · Menstrual Cycle Tracking
112 interventions · 14 stacks
- health
Insulin Sensitivity Improvement
Top: Adequate Protein Intake · Ayurveda · Bilberry Extract
111 interventions · 21 stacks
- health
Improve Heart Rate Variability (HRV)
Top: Cold Water Face Plunge · Heat Exposure (Sauna/Steam) · Shiatsu Massage
110 interventions · 20 stacks
- health
Normal Blood Pressure Support
Top: 4-7-8 Breathing Technique · Acupressure · Acupuncture
110 interventions · 21 stacks
- body
Muscle Relaxation
Top: Kripalu Yoga · 5Rhythms Dance · Acupuncture
109 interventions · 13 stacks
- psyche
Antidepressant Effect
Top: 5-HTP · Bromantane · Alternate Nostril Breathing
108 interventions · 18 stacks
- health
Digestion Improvement
Top: Magnesium · Artichoke Extract · Avoiding Heavy Meals Before Bed
108 interventions · 19 stacks
- body
Physical Energy Boost
Top: Shilajit · Yohimbine · Bhastrika Pranayama
108 interventions · 21 stacks
- health
Weight Management Support
Top: Carb Cycling · 5-HTP · Ayurveda
108 interventions · 19 stacks
- health
Blood Glucose Level Support
Top: Astaxanthin · Benfotiamine · Bilberry Extract
106 interventions · 19 stacks
- health
Skin Health Improvement
Top: Dry Brushing · Chamomile · Consume Healthy Fats
104 interventions · 21 stacks
- mind
Increased Mental Productivity
Top: Bullet Journal · CDP-Choline · Contrast Shower
104 interventions · 17 stacks
- health adverse
Tachycardia
Increase in heart rate above normal (usually >100 beats per minute at rest). May be felt as strong palpitations, cause discomfort, shortness of breath, or dizziness.
104 interventions · 0 stacks
- health adverse
Constipation
Difficult, infrequent (less than 3 times a week), or incomplete bowel evacuation, often accompanied by hard stools and the need to strain.
102 interventions · 0 stacks
- psyche adverse
Depression
Occurrence or worsening of symptoms of depression (sadness, loss of interest, apathy) during supplement intake. May be related to effects on neurotransmitters or hormonal balance.
101 interventions · 0 stacks
- health
Joint Health Improvement
Top: Astaxanthin · BPC-157 · Contact Improvisation
101 interventions · 21 stacks
- psyche
Irritability Reduction
Top: Bhakti Yoga · Cycle Syncing · Free / Intuitive Dance
99 interventions · 16 stacks
- body
Physical Endurance Increase
Top: Bhastrika Pranayama · Iron · Iyengar Yoga
98 interventions · 19 stacks
- health adverse
Increased Sweating
Excessive sweat production (hyperhidrosis), not related to an adequate response to temperature or physical exertion. Can be caused by stimulants, thermogenics, or effects on the autonomic nervous system.
98 interventions · 0 stacks
- health adverse
Increased Blood Pressure (Hypertension)
Temporary or persistent increase in arterial blood pressure above normal values (usually >130/80 or 140/90 mmHg). Can be caused by stimulants, substances affecting blood vessels or fluid retention.
97 interventions · 0 stacks
- mind
Increase Mental Endurance
Top: Bhastrika Pranayama · Bromantane · Guarana
97 interventions · 18 stacks
- health
Cellular Energy Support
Top: Alpha-Lipoic Acid · Avoid Processed Foods · Bhastrika Pranayama
96 interventions · 22 stacks
- mind adverse
Difficulty Concentrating
Inability to focus on a task, easy distractibility, absent-mindedness, occurring as a side effect.
92 interventions · 0 stacks
- health adverse
Hypotension
Decrease in arterial blood pressure below normal values, which can cause weakness, dizziness, darkening of vision, fainting.
92 interventions · 0 stacks
- health
Liver Health Support
Top: Calcium D-Glucarate · Dandelion Root · Ergothioneine
92 interventions · 19 stacks
- health adverse
Heartburn / Reflux
A burning sensation behind the breastbone or in the upper abdomen, often rising towards the throat, caused by the backflow of acidic stomach contents into the esophagus (reflux). May be accompanied by a sour taste in the mouth.
89 interventions · 0 stacks
- body
Muscle Recovery Acceleration
Top: Astaxanthin · BPC-157 · Bromelain
88 interventions · 17 stacks
- body adverse
Dry Mouth (Xerostomia)
Feeling of dryness in the oral cavity due to insufficient saliva production. Can cause discomfort, difficulty swallowing, and increase the risk of cavities.
85 interventions · 0 stacks
- body
Flexibility Improvement
Top: Belly Dance · Calisthenics · Chiropractic
84 interventions · 15 stacks
- body adverse
Muscle Cramps
Involuntary, sharp, and painful contractions of muscles or muscle groups, often in the legs. May be related to electrolyte imbalance or neuromuscular transmission issues.
84 interventions · 0 stacks
- health adverse
Vomiting
Reflex ejection of stomach contents through the mouth. Can be caused by GI irritation, high dose, unpleasant taste/smell of the supplement, or as part of general intoxication.
84 interventions · 0 stacks
- mind
Increase Alertness
Top: Aromatherapy · Bhastrika Pranayama · Bhastrika Pranayama
82 interventions · 14 stacks
- health
Longevity and Anti-Aging Support
Top: Taurine · Acetyl-L-Carnitine (ALCAR) · Fisetin
81 interventions · 18 stacks
- health
Respiratory System Support
Top: Andrographis · Black Elderberry · Black Seed Oil
77 interventions · 14 stacks
- health adverse
Paresthesia (Tingling, Numbness)
Abnormal skin sensations such as tingling ('pins and needles'), burning, numbness, or formication ('crawling ants') without apparent cause. Often temporary (e.g., from niacin or beta-alanine).
72 interventions · 0 stacks
- psyche adverse
Appetite Changes (Undesirable)
Uncontrolled and undesirable increase (increased appetite leading to overeating) or decrease (loss of appetite leading to undereating) in the feeling of hunger as a side effect.
71 interventions · 0 stacks
- health
Bone Health Improvement
Top: High-Intensity Interval Training (HIIT) · Ligandrol LGD-4033 · Avoid Processed Foods
71 interventions · 19 stacks
- health
Cholesterol Level Reduction
Top: Ayurveda · Black Seed Oil · Chlorella
71 interventions · 19 stacks
- mind
Motivation Increase
Top: Acceptance and Commitment Therapy · Adrafinil · Bromantane
68 interventions · 14 stacks
- health adverse
Tremor (Shaking)
Involuntary rhythmic oscillating movements of body parts, most often the hands, less commonly the head or voice. Often associated with stimulant intake.
67 interventions · 0 stacks
- body
Fat Burning Enhancement
Top: Avoid Processed Foods · Caffeine · Cryotherapy Chamber / Whole Body Cryotherapy
65 interventions · 16 stacks
- body
Improve Balance
Top: Belly Dance · Bikram Yoga · Ecstatic Dance
64 interventions · 12 stacks
- psyche adverse
Decreased Libido
Weakening or loss of sexual desire and interest in sexual activity as an undesirable side effect.
64 interventions · 0 stacks
- body
Improve Posture
Top: 5Rhythms Dance · Ballet Fitness · Belly Dance
60 interventions · 11 stacks
- body adverse
Weakness
General feeling of physical weakness, lack of strength, easy fatigability, making it difficult to perform usual activities.
60 interventions · 0 stacks
- health
Detoxification Process Support
Top: Chlorella · Dandelion Root · Spirulina
59 interventions · 12 stacks
- health
Gut-Brain Axis Support
Top: Acupressure · Ashwagandha · Ayurveda
57 interventions · 16 stacks
- mind adverse
Decreased Motivation
Lack of energy, lack of desire to do anything, loss of interest in activities that previously brought pleasure, decreased purposefulness.
56 interventions · 0 stacks
- mind adverse
Apathy
A state of emotional indifference, lack of interest in life, work, hobbies, communication. Characterized by decreased motivation, initiative, and emotional reactions.
55 interventions · 0 stacks
- body
Physical Strength Increase
Top: Ligandrol LGD-4033 · Carb Cycling · Hatha Yoga
55 interventions · 13 stacks
- health adverse
Weight Gain (Undesirable)
Increase in body weight (due to fat or fluid retention) that is not the intended goal of taking the supplement.
55 interventions · 0 stacks
- body
Workout Efficiency Enhancement
Top: Ballet Fitness · Carb Cycling · D-Ribose
54 interventions · 14 stacks
- psyche
Dopamine System Support
Top: Free / Intuitive Dance · 5Rhythms Dance · Animal Flow
54 interventions · 14 stacks
- health adverse
Hypoglycemia
Decrease in blood sugar (glucose) levels below normal values. Can manifest as weakness, sweating, trembling, dizziness, confusion, in severe cases - loss of consciousness. Risk with supplements that lower sugar, especially in combination with anti-diabetic drugs.
51 interventions · 0 stacks
- body
Tissue Elasticity Enhancement
Top: Deep Tissue Massage · DMAE · Ecstatic Dance
50 interventions · 13 stacks
- body
Wound Healing Acceleration
Top: Chymotrypsin · Herbalism / Phytotherapy · MSM
50 interventions · 11 stacks
- health adverse
Vision Problems
Various visual disturbances: blurred or cloudy vision, double vision (diplopia), changes in color perception, appearance of 'floaters' or flashes, increased sensitivity to light (photophobia).
50 interventions · 0 stacks
- psyche
Sleep Onset Improvement
Top: Amanita Pantherina · Chamomile · Ethanol (alcohol)
49 interventions · 13 stacks
- health adverse
Menstrual Cycle Changes
Irregularities (delays, premature periods), changes in duration, flow intensity, or painfulness of menstruation, intermenstrual bleeding.
49 interventions · 0 stacks
- health
Biorhythm Regulation
Top: Cycle Syncing · Tryptophan · Vitex Agnus-Castus
49 interventions · 15 stacks
- health adverse
Increased Thirst and Urination
Increased thirst (polydipsia) and increased urine output (polyuria), not related to adequate fluid intake. Can be a sign of water-salt imbalance or kidney function issues.
49 interventions · 0 stacks
- psyche adverse
Confusion
A state of disorientation in time or space, difficulty concentrating, slowed or illogical thinking, problems with decision-making. Can be a temporary side effect, especially at high doses or with individual sensitivity.
48 interventions · 0 stacks
- body adverse
Muscle Spasms (Not Cramps)
Less intense but often repetitive involuntary muscle contractions or twitches.
47 interventions · 0 stacks
- psyche adverse
Dependence
Formation of a physical or psychological need for regular intake of a supplement to maintain normal well-being or achieve the desired effect, accompanied by withdrawal syndrome upon cessation.
45 interventions · 0 stacks
- body adverse
Decreased Physical Endurance
Reduced ability to perform physical work for a long time, faster onset of fatigue during exertion.
45 interventions · 0 stacks
- health
Nutrient Deficiency Replenishment
Top: Lipase · Nutrition Tracking · Amylase
45 interventions · 16 stacks
- health adverse
Gastritis (Stomach Irritation)
Inflammation or irritation of the stomach lining, manifesting as upper abdominal pain, nausea, discomfort. Can be triggered by supplements that irritate the mucosa (iron, potassium, NSAID-like) or increase acidity.
44 interventions · 0 stacks
- body
Oxygen Utilization Improvement
Top: Bhastrika Pranayama · Nicotinamide Mononucleotide (NMN) · Shilajit
44 interventions · 10 stacks
- health
DNA Damage Protection
Top: Alpha-Lipoic Acid · Avoid Processed Foods · Fasting Mimicking Diet
43 interventions · 14 stacks
- health
Sexual Function and Libido Improvement
Top: Tribulus Terrestris · Anastrozole · Cabergoline
42 interventions · 14 stacks
- psyche
Social Function Improvement
Top: Free / Intuitive Dance · Kava Kava · Propranolol
42 interventions · 3 stacks
- body
Appetite Suppression
Top: 5-HTP · Mindless Snacking · Modafinil
41 interventions · 10 stacks
- body
Muscle Mass Increase
Top: Ligandrol LGD-4033 · Carb Cycling · High-Intensity Interval Training (HIIT)
41 interventions · 10 stacks
- health adverse
Nutrient Deficiency
Development of an insufficiency of one or more essential nutrients (vitamins, minerals, etc.) in the body, caused by taking a supplement. Can occur due to impaired nutrient absorption (e.g., zinc interfering with copper), increased excretion, increased requirement, or direct antagonism.
41 interventions · 0 stacks
- health
Lymphatic System Support
Top: Osteopathy · Self-Cupping Massage (Silicone) · Shiatsu Massage
41 interventions · 2 stacks
- mind
Increase Reaction Speed
Top: Contact Improvisation · Animal Flow · Ballet Fitness
40 interventions · 9 stacks
- body adverse
Muscle Weakness
Decrease in muscle strength, feeling of lethargy, and difficulty performing movements requiring muscular effort. Can be caused by electrolyte imbalance (potassium, magnesium), effects on neuromuscular transmission, or direct muscle damage.
40 interventions · 0 stacks
- health
Autophagy Support
Top: Herbal Steam Bath · Intermittent Calorie Restriction · Intermittent Fasting
40 interventions · 12 stacks
- body
Muscle Mass Preservation
Top: Carb Cycling · High-Intensity Interval Training (HIIT) · Ligandrol LGD-4033
40 interventions · 13 stacks
- health adverse
Blood Thinning (Bleeding Risk)
Decreased blood clotting ability (anticoagulant or antiplatelet effect), increasing the risk of bleeding, especially with injuries, surgeries, or concomitant use of other 'blood-thinning' drugs.
39 interventions · 0 stacks
- psyche
Serotonin System Support
Top: 5Rhythms Dance · Animal Flow · Ecstatic Dance
39 interventions · 13 stacks
- health adverse
Hormonal Imbalance
Disruption of the normal ratio or levels of various hormones (sex hormones, thyroid, adrenal) caused by supplement intake affecting their synthesis, metabolism, or receptors.
38 interventions · 0 stacks
- health
Eye Health and Vision Support
Top: Mindless Scrolling on Devices · Rutin · Coenzyme Q10
37 interventions · 16 stacks
- health
Male Fertility Improvement
Top: Ayurveda · Cycle Symptom Logging · Arginine
36 interventions · 14 stacks
- health adverse
Erectile Dysfunction
Occurrence or worsening of problems with achieving or maintaining an erection during supplement intake.
34 interventions · 0 stacks
- mind adverse
Tolerance Development
Gradual decrease in the effect of a supplement at the same dose, requiring an increase in dosage to achieve the original result. Can lead to the risk of overdose and dependence.
34 interventions · 0 stacks
- health adverse
Increased Liver Load
Increased workload on the liver required to metabolize and eliminate supplement components. With long-term use or high doses, can lead to elevated liver enzymes (ALT, AST) and risk of hepatotoxicity.
33 interventions · 0 stacks
- health adverse
Worsen Lipid Profile
Negative change in blood lipid levels (e.g., increased LDL, triglycerides, or decreased HDL), increasing the risk of cardiovascular diseases.
32 interventions · 0 stacks
- psyche adverse
Depersonalization
Subjective feeling of detachment or unreality regarding one's own self, thoughts, feelings, body, or actions. A person may feel like a robot, an outside observer of their life, 'not in their own body', or that their emotions are blunted/do not belong to them. Often occurs together with derealization as part of a dissociative experience.
31 interventions · 0 stacks
- body
Acne Reduction
Top: Avoid Processed Foods · Mindless Snacking · Astaxanthin
31 interventions · 12 stacks
- health adverse
Hepatotoxicity (Liver Damage)
Toxic effect of a supplement or its metabolites on liver cells (hepatocytes), leading to their damage or death. May manifest as elevated liver enzymes, jaundice, impaired liver function.
30 interventions · 0 stacks
- body
Morning Alertness Improvement
Top: Ayurveda · Free / Intuitive Dance · Histidine
30 interventions · 10 stacks
- health
Fatty Liver Disease Prevention
Top: Coenzyme Q10 · Fibers (prebiotics) · Inositol
30 interventions · 16 stacks
- health
Muscle Spasm Support
Top: Glycine · Heating Pads / Warm Compresses · Herbal Steam Bath
30 interventions · 13 stacks
- psyche adverse
Derealization
Subjective feeling of unreality, detachment, or distortion of the surrounding world. The environment, people, or objects may be perceived as artificial, foggy, flat, lifeless, or dreamlike. It is one of the dissociative symptoms, can accompany anxiety states, or be a side effect of psychoactive substances.
29 interventions · 0 stacks
- health
Collagen Production Stimulation
Top: Animal Flow · Calisthenics · Grape Seed Extract
29 interventions · 11 stacks
- mind
Creativity Boost
Top: 5Rhythms Dance · Active Music Making · Ambient Music Listening
29 interventions · 4 stacks
- body adverse
Acne
Appearance or worsening of acne (pimples, comedones) on the face, back, or chest, often related to hormonal changes caused by the supplement.
28 interventions · 0 stacks
- health adverse
Increased Inflammation
Paradoxical increase in inflammation markers (e.g., CRP) or worsening of symptoms of inflammatory diseases while taking the supplement.
28 interventions · 0 stacks
- health adverse
Seizure Disorders (Risk / Provocation)
Increased risk of seizures or lowering of the seizure threshold in predisposed individuals. May be associated with excessive CNS stimulation, effects on neurotransmitter balance (e.g., reduced GABA), or toxic effects.
28 interventions · 0 stacks
- mind adverse
Cognitive Decline
Noticeable decrease in abilities for memorization, learning, concentration, thinking speed, or problem-solving compared to baseline, caused by supplement intake.
27 interventions · 0 stacks
- body
Metabolic Flexibility Improvement
Top: Finnish Sauna · Green Tea Extract · Jivamukti Yoga
27 interventions · 13 stacks
- health
Testosterone Level Increase
Top: Ashwagandha · Cabergoline · Cistanche Tubulosa
27 interventions · 11 stacks
- mind
Acetylcholine System Support
Top: DMAE · Herbalism / Phytotherapy · Jivamukti Yoga
27 interventions · 4 stacks
- body adverse
Dry Skin
Increased dryness, flaking, tightness, or itching of the skin. Can be caused by supplement intake, especially in high doses or with prolonged use (e.g., hypervitaminosis A).
26 interventions · 0 stacks
- health
Male Vitality Support
Top: Anastrozole · Ashwagandha · Herbalism / Phytotherapy
26 interventions · 13 stacks
- psyche adverse
Excessive Appetite Suppression
Undesirable and strong reduction in the feeling of hunger, leading to insufficient food intake, potential weight loss (if unintended), and nutrient deficiencies. A side effect of some stimulants or serotonergic agents.
25 interventions · 0 stacks
- body adverse
Hair Loss (Alopecia)
Increased hair shedding, leading to thinning hair or bald patches. May be related to hormonal changes or toxic effects.
25 interventions · 0 stacks
- body
Hair Strengthening
Top: Rosemary Extract · Collagen Peptides · MSM
25 interventions · 11 stacks
- health adverse
Increased Insulin Resistance
Decreased sensitivity of cells to insulin, leading to impaired glucose metabolism and increased risk of developing type 2 diabetes, caused by supplement intake.
25 interventions · 0 stacks
- health adverse
Increased Concentration of Drugs
Increases the concentration of certain other concurrently taken drugs or supplements in the blood by slowing their metabolism, potentially enhancing their effects and side effects.
24 interventions · 0 stacks
- health
Antiviral Effect
Top: Black Elderberry · Turkey Tail · Astragalus
24 interventions · 8 stacks
- health
Increased Growth Hormone Release
Top: High-Intensity Interval Training (HIIT) · Heat Exposure (Sauna/Steam) · Mindless Snacking
24 interventions · 7 stacks
- health
Female Hormonal Balance Support
Top: Cabergoline · Calcium D-Glucarate · Cycle Syncing
24 interventions · 9 stacks
- health adverse
Taste Disorders (Dysgeusia)
Alteration of taste sensations, appearance of a metallic, bitter, or other unpleasant taste in the mouth, or reduced ability to distinguish tastes. May be caused by the supplement's effect on taste receptors or their innervation.
24 interventions · 0 stacks
- body adverse
Fluid Retention (Edema)
Excessive accumulation of fluid in body tissues, leading to swelling (most often of the legs, ankles, face, hands), weight gain, and a feeling of 'bloatedness'.
23 interventions · 0 stacks
- health
Allergy Symptom Relief
Top: Black Seed Oil · MSM · Rutin
21 interventions · 7 stacks
- health adverse
Gout Flare-up
Occurrence or intensification of a gout attack - acute inflammation of a joint (most often the big toe), caused by the deposition of uric acid crystals, triggered by supplement intake.
21 interventions · 0 stacks
- health
Erectile Function Support
Top: Cabergoline · Pycnogenol · Shilajit
21 interventions · 11 stacks
- health
Oral Health Support
Top: Mindless Snacking · Consume Probiotics · Deglycyrrhizinated Licorice (DGL)
21 interventions · 10 stacks
- health adverse
Hyperglycemia
Increase in blood sugar (glucose) levels above normal values, which can be dangerous for people with diabetes or predisposition to it.
20 interventions · 0 stacks
- health adverse
Kidney Dysfunction
Impaired ability of the kidneys to filter blood, excrete metabolic products, and maintain water-electrolyte balance. May manifest as changes in urine and blood tests (increased creatinine, urea), edema.
20 interventions · 0 stacks
- health
Prostate Health Support
Top: High-Fiber and Vegetable Diet · Astaxanthin · Diindolylmethane (DIM)
20 interventions · 9 stacks
- health adverse
Bradycardia
Slowing of the heart rate below normal (usually less than 60 beats per minute). May manifest as weakness, dizziness, fatigue.
18 interventions · 0 stacks
- body adverse
Fluid Loss (Diuretic Effect)
Significant loss of body fluid due to the pronounced diuretic action of the supplement, which can lead to dehydration, electrolyte imbalance, and weight loss due to water (often temporary).
18 interventions · 0 stacks
- health
Kidney Health Support
Top: Dandelion Root · Ergothioneine · Cordyceps
18 interventions · 8 stacks
- health
Nausea Relief Support
Top: Elimination Diet · Naturopathy · Aromatherapy
18 interventions · 4 stacks
- body
Skin Protection from UV Radiation
Top: Grape Seed Extract · Lutein · Pycnogenol
17 interventions · 5 stacks
- body
Nail Strengthening
Top: Collagen Peptides · MSM · Silica
17 interventions · 10 stacks
- health adverse
Mineral Imbalance
Imbalance between different minerals in the body (e.g., calcium/magnesium, zinc/copper, sodium/potassium) due to excessive intake of one mineral, which can impair the absorption or function of another.
17 interventions · 0 stacks
- health adverse
Decreased Bone Density
Reduction in bone mineral density, making bones more brittle and increasing the risk of fractures (osteoporosis). May be related to impaired calcium metabolism or hormonal imbalance.
16 interventions · 0 stacks
- health adverse
Rhinitis
Inflammation of the nasal mucous membrane, manifesting as a runny nose, nasal congestion, and sneezing. Can be a side effect of some medications.
16 interventions · 0 stacks
- health adverse
Anemia
Decrease in hemoglobin and/or red blood cell levels in the blood below normal, leading to impaired oxygen transport. Can be caused by supplements that interfere with the absorption of iron, vitamin B12, or folic acid, or cause hemolysis (red blood cell destruction). Manifests as weakness, fatigue, paleness, shortness of breath.
15 interventions · 0 stacks
- health
Antifungal Effect
Top: Garlic · Herbalism / Phytotherapy · MCT Oil
15 interventions · 9 stacks
- psyche adverse
Undesirable Increase in Libido
Excessive, obsessive, or inappropriate increase in sexual desire or activity, causing discomfort or problems in social life.
15 interventions · 0 stacks
- health
Jet Lag Symptom Relief
Top: Adrafinil · Modafinil · Consistent Sleep Schedule
15 interventions · 6 stacks
- health
Anticonvulsant Effect
Top: EEG Neurofeedback · Transcranial Brain Stimulation · Black Seed Oil
14 interventions · 5 stacks
- health adverse
Kidney Stones (Formation Risk)
Increased risk of forming hard deposits (stones) in the kidneys, most commonly calcium oxalate, urate, or phosphate. May be associated with excessive intake of calcium, vitamin D (causing hypercalcemia), vitamin C (metabolizes to oxalates), or substances increasing uric acid levels. Manifests as severe flank pain, blood in urine.
14 interventions · 0 stacks
- health
Homocysteine Level Reduction
Top: Lecithin · Betaine (TMG) · SAM-e
14 interventions · 7 stacks
- health
Thyroid Health Support
Top: Herbalism / Phytotherapy · Red Light Therapy · Ashwagandha
14 interventions · 12 stacks
- health
Diuretic Effect
Top: Caffeine · Herbalism / Phytotherapy · Horse Chestnut Extract
13 interventions · 2 stacks
- health adverse
Heavy Metal Accumulation
Gradual buildup of toxic metals (mercury, lead, cadmium, arsenic) in body tissues due to their presence in low-quality supplements (especially of plant or marine origin). Can lead to chronic intoxication.
13 interventions · 0 stacks
- health adverse
Hypokalemia
Decrease in blood potassium levels below normal (<3.5 mmol/L). Can be caused by taking diuretics (non-potassium-sparing), laxatives, licorice root (glycyrrhizin), insufficient potassium intake, or losses through vomiting/diarrhea. Manifests as muscle weakness, cramps, heart rhythm disturbances, constipation.
13 interventions · 0 stacks
- body
Increased Appetite
Top: Zinc · Alcohol Consumption · Acupuncture
12 interventions · 5 stacks
- health
Female Fertility Improvement
Top: Cabergoline · Vitex Agnus-Castus · Coenzyme Q10
12 interventions · 12 stacks
- health
Bioavailability Improvement
Top: Papain · Apigenin · Boswellia
12 interventions · 4 stacks
- health adverse
Neuropathy
Damage to peripheral nerves, manifesting as pain, burning, tingling, numbness, weakness, or sensory disturbance, most often in the extremities. Can be caused by toxic effects or deficiency/excess of certain vitamins (e.g., B6).
12 interventions · 0 stacks
- body adverse
Increased Photosensitivity
Increased sensitivity of the skin to ultraviolet radiation, leading to quicker and easier occurrence of sunburn, redness, or rash upon sun exposure.
12 interventions · 0 stacks
- psyche adverse
Rebound Depression
Occurrence or worsening of depressive symptoms (depressed mood, apathy, anhedonia) after stopping a supplement that had a stimulating or antidepressant effect.
12 interventions · 0 stacks
- psyche adverse
Suppression of Hormone Production
Decrease in the body's own (endogenous) production of hormones (e.g., testosterone, cortisol) in response to the intake of exogenous hormones or substances affecting their regulation. Can lead to hormonal imbalance after withdrawal.
11 interventions · 0 stacks
- health adverse
Hypoandrogenism (Decreased Androgens)
A condition characterized by low levels of male sex hormones (androgens, primarily testosterone) or reduced effects, caused by supplement intake.
11 interventions · 0 stacks
- psyche adverse
Hallucinations
Perception of non-existent objects, sounds, or sensations (visual, auditory, tactile). It is a rare and serious side effect, possible with the intake of certain psychoactive substances or significant overdose.
10 interventions · 0 stacks
- body
Taste Sensitivity Improvement
Top: Avoid Sugar · Copper · Mindless Snacking
10 interventions · 7 stacks
- health
Urinary Flow Improvement
Top: Saw Palmetto · Acupressure · Acupuncture
10 interventions · 1 stacks
- body adverse
Fishy Body Odor
Appearance of an unpleasant body odor resembling fish. Often related to impaired metabolism of choline or carnitine and accumulation of trimethylamine (TMA).
10 interventions · 0 stacks
- health adverse
Increased Prolactin Levels
Increase in the concentration of the hormone prolactin in the blood, which can lead to menstrual cycle disorders, galactorrhea (milk discharge), decreased libido, erectile dysfunction.
10 interventions · 0 stacks
- health adverse
Stool Color Change
Alteration in the normal color of feces, such as darkening to black when taking iron supplements. Usually harmless but a noticeable effect.
10 interventions · 0 stacks
- health
Electrolyte Balance Support
Top: Zinc · Adequate Hydration · Calcium
10 interventions · 15 stacks
- health
Hemoglobin Level Support
Top: Spirulina · Chlorella · Recreational Sports
10 interventions · 2 stacks
- body
Hydration Support
Top: Betaine (TMG) · Adequate Hydration · High-Fiber and Vegetable Diet
10 interventions · 8 stacks
- health
Antibiotic Recovery
Top: Fibers (prebiotics) · High-Fiber and Vegetable Diet · Glutamine
9 interventions · 4 stacks
- health
Eye Protection from Blue Light
Top: Blueberry Extract · Pycnogenol · Astaxanthin
9 interventions · 1 stacks
- health adverse
Hypothyroidism
Development or worsening of symptoms of decreased thyroid function (fatigue, weight gain, cold intolerance, constipation, depression) when taking supplements that block the synthesis or action of thyroid hormones (e.g., large doses of certain goitrogens).
9 interventions · 0 stacks
- body
Heat Tolerance Improvement
Top: Bikram Yoga · Power Yoga · Heat Exposure (Sauna/Steam)
9 interventions · 0 stacks
- health
Improve Iron Absorption
Top: Betaine (TMG) · Consume Probiotics · Histidine
9 interventions · 3 stacks
- body adverse
Nail Changes
Undesirable changes in the appearance or structure of nails: brittleness, splitting, discoloration (yellowing, darkening), appearance of ridges or spots, slowed growth. Can be caused by nutrient deficiency/excess or toxic effects.
9 interventions · 0 stacks
- body adverse
Garlic Breath/Body Odor
Appearance of a characteristic garlic or sulfur smell from the mouth or skin, related to the metabolism of sulfur compounds contained in some supplements (e.g., MSM, garlic).
9 interventions · 0 stacks
- health
SHBG Level Reduction
Top: DHEA · Inositol · Nettle Root
8 interventions · 1 stacks
- health adverse
Ejaculation Disorder
Disorders of the ejaculation process: premature, delayed, retrograde (sperm enters the bladder) ejaculation, or anorgasmia (inability to achieve orgasm). A rare side effect related to effects on the nervous system or hormones.
8 interventions · 0 stacks
- health adverse
Hangover
A group of unpleasant symptoms (headache, nausea, fatigue, dehydration) following the consumption of ethanol.
8 interventions · 0 stacks
- health adverse
Increased Intestinal Permeability
Impairment of the barrier integrity between the intestinal lumen and the internal environment, allowing bacterial toxins and undigested food particles to enter the bloodstream, causing inflammation and immune reactions.
8 interventions · 0 stacks
- health adverse
Nutrient Malabsorption
Decreased ability of the intestine to absorb one or more types of nutrients (vitamins, minerals, fats, proteins, carbohydrates), which can lead to their deficiency even with adequate intake.
8 interventions · 0 stacks
- health
Resilience to Environmental Pollution Enhancement
Top: Spirulina · High-Fiber and Vegetable Diet · Rosemary Extract
8 interventions · 1 stacks
- body adverse
Hot Flashes
Sudden sensation of intense heat, often starting in the chest and face area, accompanied by skin redness and sweating. Most often associated with hormonal changes (menopause), but can be triggered by certain supplements.
7 interventions · 0 stacks
- health adverse
Increased Salivation (Hypersalivation)
Excessive saliva production. Can be caused by direct stimulation of salivary glands or be a reaction to nausea or oral irritation.
7 interventions · 0 stacks
- health
Gout Management Support
Top: Herbalism / Phytotherapy · High-Fiber and Vegetable Diet · Rutin
7 interventions · 4 stacks
- body
Travel Wellness Support
Top: Andrographis · Isochronic Tones · Modafinil
7 interventions · 2 stacks
- health
Vaginal Health Support
Top: Probiotics · Red Light Therapy · Reducing Sugar and Processed Foods
7 interventions · 7 stacks
- health adverse
Amino Acid Imbalance
Disruption of the normal ratio of various amino acids in the body due to excessive intake of one or more, which can negatively affect protein synthesis, neurotransmitters, and other metabolic pathways.
6 interventions · 0 stacks
- health adverse
LDL Cholesterol Increase
Increase in the level of low-density lipoproteins ("bad" cholesterol) in the blood, which is a risk factor for cardiovascular diseases.
6 interventions · 0 stacks
- health adverse
Histamine Release
Stimulation of histamine release from mast cells by the substance itself (non-allergic mechanism), which can cause allergy-like symptoms (itching, skin redness, runny nose, drop in blood pressure).
6 interventions · 0 stacks
- health
Lactation Enhancement
Top: Fenugreek Extract · Herbalism / Phytotherapy · Acupressure
6 interventions · 1 stacks
- health
Prolactin Level Reduction
Top: Vitamin B6 · Cabergoline · Vitex Agnus-Castus
5 interventions · 2 stacks
- health adverse
Histamine Intolerance Trigger
Worsening of symptoms in people with pre-existing histamine intolerance (headache, rash, diarrhea, runny nose) due to histamine content in the supplement or its ability to block the DAO enzyme.
5 interventions · 0 stacks
- health adverse
Hypermagnesemia
Elevated magnesium levels in the blood above the normal range (>1.1-1.3 mmol/L). Can be caused by excessive intake of magnesium supplements, especially with kidney failure. Manifests as muscle weakness, decreased reflexes, hypotension, nausea, heart rhythm disturbances, and in severe cases - respiratory depression and cardiac arrest.
5 interventions · 0 stacks
- health adverse
Hyperthyroidism
Development or worsening of symptoms of increased thyroid function (rapid heartbeat, sweating, weight loss, tremor, anxiety) when taking supplements containing iodine or stimulating the thyroid gland.
5 interventions · 0 stacks
- body
Cold Resistance Improvement
Top: Cold Exposure · Cold Shower · Contrast Shower
5 interventions · 2 stacks
- health adverse
Prostate Hyperplasia (Stimulation)
Stimulation of prostate tissue growth, which can lead to the development or worsening of benign prostatic hyperplasia (BPH) and associated urinary problems.
5 interventions · 0 stacks
- body
High Altitude Adaptation
Top: Cordyceps · Ginger · Phenylpiracetam (Phenotropil)
5 interventions · 1 stacks
- health
Ear and Hearing Health Support
Top: Red Light Therapy · Coenzyme Q10 · Ginkgo Biloba
5 interventions · 3 stacks
- health adverse
Anaphylactoid Reaction
Severe, rapid systemic reaction similar to anaphylaxis (drop in blood pressure, bronchospasm, edema), but developing through a different mechanism (not always IgE-mediated), e.g., direct histamine release.
4 interventions · 0 stacks
- health adverse
Fever / Elevated Temperature
Increase in body temperature above normal values (usually >37.2-37.5°C or 99-99.5°F), as a possible, though rare, side effect, often as part of a systemic reaction (allergy, inflammation).
4 interventions · 0 stacks
- health adverse
Increased Homocysteine Levels
Increase in the concentration of the amino acid homocysteine in the blood, which is a risk factor for cardiovascular diseases. Paradoxically, can be caused not only by B-vitamin deficiency but also by excess methionine or the influence of certain substances.
4 interventions · 0 stacks
- health adverse
Hyperkalemia
Increase in blood potassium levels above normal. Can be dangerous, causing muscle weakness, heart rhythm disturbances, up to cardiac arrest. Risk is increased with potassium supplements, especially with kidney failure or use of potassium-sparing diuretics.
4 interventions · 0 stacks
- health
Seasonal Adaptation Support
Top: Herbalism / Phytotherapy · SAD Lamp Light Therapy · Echinacea
4 interventions · 1 stacks
- health adverse
Copper Deficiency
Reduction of copper levels in the body below normal, caused by prolonged intake of high doses of zinc, which competes for absorption. Copper deficiency can lead to anemia (resistant to iron treatment), neutropenia, osteoporosis, and neurological problems.
3 interventions · 0 stacks
- health adverse
Hypercalcemia
Elevated calcium levels in the blood above normal. Can be caused by excessive intake of vitamin D and/or calcium. Symptoms: thirst, frequent urination, constipation, nausea, weakness, confusion, risk of kidney stones.
3 interventions · 0 stacks
- body
Olfaction Improvement
Top: Histidine · Mindful Eating · Zinc
3 interventions · 5 stacks
- body adverse
Joint Pain (Arthralgia)
Appearance or worsening of pain in one or more joints, not related to injury or existing disease.
3 interventions · 0 stacks
- body
Hair Pigmentation Support
Top: Copper · Catalase · Phenylalanine
3 interventions · 0 stacks
- health adverse
Dyskinesia
Impaired coordination, involuntary movements (e.g., tics, chorea, athetosis). A rare side effect, more characteristic of antipsychotics, but theoretically possible with strong effects on the dopamine system.
2 interventions · 0 stacks
- body adverse
Kava Dermopathy
Specific skin condition characterized by dryness, scaling, yellowish or grayish skin discoloration, especially on the palms and soles. Associated with long-term and/or excessive consumption of kava (Piper methysticum).
2 interventions · 0 stacks
- body adverse
Maple Syrup Urine/Sweat Odor
Appearance of a specific sweetish odor of urine or sweat resembling maple syrup. May be associated with fenugreek intake or impaired amino acid metabolism.
2 interventions · 0 stacks
- health adverse
Increased Ammonia Levels
Increase in the concentration of ammonia in the blood, which is a toxic product of protein metabolism. High ammonia levels can negatively affect brain function.
1 interventions · 0 stacks
- health adverse
Fibromyalgia
Onset or worsening of fibromyalgia symptoms, such as chronic widespread pain, fatigue, sleep disturbances, and cognitive difficulties, as a possible side effect.
1 interventions · 0 stacks
- health adverse
Fungemia
Presence of fungi (most commonly yeast, e.g., Candida) in the bloodstream. This is a serious condition that may occur in immunocompromised patients taking certain probiotics (especially Saccharomyces boulardii).
1 interventions · 0 stacks
- health adverse
Heart Valve Damage
Structural changes in heart valves (thickening, insufficiency), leading to impaired function. A very rare but serious side effect, historically linked to certain drugs (fenfluramine), theoretically possible with long-term use of potent serotonergic agents.
1 interventions · 0 stacks
- health adverse
Masking B12 Deficiency
Taking high doses of folic acid can correct the megaloblastic anemia caused by vitamin B12 deficiency, but does not address the B12 deficiency itself. This is dangerous because neurological damage due to lack of B12 can progress unnoticed, becoming irreversible.
1 interventions · 0 stacks
- health adverse
Eosinophilia-Myalgia Syndrome (EMS)
A rare but potentially fatal disease characterized by abnormally high levels of eosinophils in the blood, severe muscle pain (myalgia), and other systemic manifestations. Historically associated with a contaminated batch of L-tryptophan.
0 interventions · 0 stacks