Effects · health adverse
Digestive Discomfort
A general term covering various unpleasant sensations in the gastrointestinal tract: heaviness, abdominal pain or cramps, heartburn, nausea, belching, flatulence, not associated with a specific diagnosis.
- Supplements
- 189
- Practices
- 49
- Habits
- 47
How we rate evidence
Probability — how likely the effect is to show up
- Very high
- High
- Medium
- Low
Evidence — where the data comes from
- Scientific Meta-analyses and randomized trials
- Clinical Clinical trials and practice
- Animal research Animal studies
- People reports User reports and anecdotes
- Theoretical Mechanistic reasoning, not yet tested
Reported as a side effect of (285)
Probability Very high 5 High 27 Medium 79 Low 174
Evidence Clinical 76 People reports 199 Theoretical 10
- Acetyl-L-Carnitine (ALCAR) Supplements MediumPeople reports
- Agmatine Sulfate Supplements LowPeople reports
- Alpha-GPC Supplements LowPeople reports
- Alpha-Lipoic Acid Supplements LowClinical
- Amylase Supplements LowPeople reports
- Andrographis Supplements LowClinical
- Apigenin Supplements LowPeople reports
- Artichoke Extract Supplements LowClinical
- D-Aspartic Acid Supplements LowPeople reports
- Astaxanthin Supplements LowPeople reports
- Bacopa Monnieri Supplements MediumClinical
- BCAA Supplements LowPeople reports
- Benfotiamine Supplements LowPeople reports
- Berberine Supplements MediumTheoretical
- Beta-Sitosterol Supplements MediumClinical
- Betaine (TMG) Supplements LowPeople reports
- Bilberry Extract Supplements LowPeople reports
- Bitter Melon Extract Supplements MediumPeople reports
- Black Elderberry Supplements LowPeople reports
- Blueberry Extract Supplements LowPeople reports
- Boron Supplements LowPeople reports
- Boswellia Supplements LowClinical
- Bromantane Supplements LowPeople reports
- Bromelain Supplements HighTheoretical
- Butyrate Supplements MediumPeople reports
- Calcium Alpha-Ketoglutarate Supplements MediumPeople reports
- Calcium D-Glucarate Supplements LowPeople reports
- Calcium Supplements LowPeople reports
- CBD Supplements MediumClinical
- Catalase Supplements LowPeople reports
- CDP-Choline Supplements LowPeople reports
- Cellulase Supplements LowPeople reports
- Cerebrolysin Supplements LowClinical
- Chaga Supplements LowPeople reports
- Chamomile Supplements LowPeople reports
- Chlorella Supplements MediumPeople reports
- Chondroitin Sulfate Supplements MediumClinical
- Chymotrypsin Supplements LowClinical
- Cinnamon Extract Supplements LowPeople reports
- Cissus Quadrangularis Supplements LowPeople reports
- Cistanche Tubulosa Supplements LowPeople reports
- Citrulline Supplements LowPeople reports
- Conjugated Linoleic Acid (CLA) Supplements MediumClinical
- Collagen Peptides Supplements LowPeople reports
- Coluracetam Supplements LowPeople reports
- Copper Supplements LowClinical
- Coenzyme Q10 Supplements LowClinical
- Cordyceps Supplements LowPeople reports
- Creatine Supplements LowPeople reports
- Curcumin Supplements LowPeople reports
- Dandelion Root Supplements MediumPeople reports
- Deglycyrrhizinated Licorice (DGL) Supplements LowPeople reports
- DHEA Supplements LowPeople reports
- Diosmin Supplements LowClinical
- DL-Phenylalanine (DLPA) Supplements LowPeople reports
- Dutasteride Supplements LowPeople reports
- EAA (Essential Amino Acids) Supplements LowPeople reports
- Ecdysterone Supplements LowPeople reports
- Echinacea Supplements LowClinical
- Eleuthero Supplements LowPeople reports
- Ethanol (alcohol) Supplements MediumTheoretical
- Eutropoflavin Supplements LowPeople reports
- Evening Primrose Oil Supplements LowPeople reports
- Fadogia Agrestis Supplements LowPeople reports
- Fenugreek Extract Supplements MediumClinical
- Fibers (prebiotics) Supplements HighTheoretical
- GABA Supplements LowPeople reports
- Garlic Supplements MediumPeople reports
- Ginger Supplements MediumPeople reports
- Ginkgo Biloba Supplements LowPeople reports
- Glucosamine Supplements LowClinical
- Glutamine Supplements MediumClinical
- Glycine Supplements LowPeople reports
- Gotu Kola Supplements LowPeople reports
- Grape Seed Extract Supplements LowPeople reports
- Green Tea Extract Supplements MediumPeople reports
- Guarana Supplements LowPeople reports
- Gymnema Sylvestre Supplements LowPeople reports
- Gynostemma Pentaphyllum Supplements LowPeople reports
- Hesperidin Supplements LowClinical
- Histidine Supplements LowPeople reports
- HMB Supplements LowPeople reports
- Honokiol Supplements LowPeople reports
- Hops Supplements LowPeople reports
- Horny Goat Weed Supplements LowPeople reports
- Horse Chestnut Extract Supplements MediumClinical
- Hyaluronic acid (HA) Supplements LowClinical
- Indole-3-Carbinol (I3C) Supplements LowPeople reports
- Inosine Supplements LowClinical
- Inositol Supplements MediumClinical
- Iodine Supplements LowPeople reports
- Iron Supplements MediumTheoretical
- Jujube Seed Extract Supplements LowPeople reports
- L-Carnitine Supplements MediumPeople reports
- L-Theanine Supplements LowPeople reports
- Lactase Supplements LowPeople reports
- Lecithin Supplements LowPeople reports
- Lemon Balm Supplements LowPeople reports
- Ligandrol LGD-4033 Supplements LowPeople reports
- Lion's Mane Supplements LowPeople reports
- Lipase Supplements LowPeople reports
- Lycopene Supplements LowPeople reports
- Lysine Supplements LowPeople reports
- Maca Root Supplements MediumPeople reports
- Magnolia Bark Extract Supplements LowPeople reports
- Maitake Supplements LowPeople reports
- Manganese Supplements LowPeople reports
- Marshmallow Root Supplements LowPeople reports
- MCT Oil Supplements HighClinical
- Melatonin Supplements LowPeople reports
- Methionine Supplements LowPeople reports
- Methylene Blue Supplements MediumPeople reports
- Milk Thistle Supplements LowClinical
- MSM Supplements MediumPeople reports
- Mucuna Pruriens (Velvet Bean) Supplements LowPeople reports
- N-Acetylcysteine (NAC) Supplements LowClinical
- N-Acetyl-L-Tyrosine (NALT) Supplements LowPeople reports
- Nattokinase Supplements LowPeople reports
- Nettle Root Supplements HighPeople reports
- Nicotinamide Mononucleotide (NMN) Supplements LowPeople reports
- Nicotine Supplements LowClinical
- NSI-189 Supplements LowPeople reports
- Olive Leaf Extract Supplements MediumPeople reports
- Omega-3 Supplements MediumClinical
- Ornithine Supplements LowPeople reports
- Oxiracetam Supplements LowPeople reports
- Palmitoylethanolamide (PEA) Supplements LowClinical
- Panax Ginseng Supplements LowPeople reports
- Papain Supplements LowPeople reports
- Passionflower Supplements LowPeople reports
- Pau d'Arco Supplements HighPeople reports
- Pelargonium sidoides Supplements LowTheoretical
- Pepsin Supplements LowPeople reports
- Phenibut Supplements MediumPeople reports
- Phenylalanine Supplements LowPeople reports
- Phosphatidylcholine (PC) Supplements MediumPeople reports
- Phosphatidylserine (PS) Supplements LowPeople reports
- Piperine Supplements LowPeople reports
- Polygala Tenuifolia Supplements LowPeople reports
- Potassium Supplements MediumPeople reports
- Pregnenolone Supplements LowPeople reports
- Proline Supplements LowPeople reports
- Protein Supplements MediumPeople reports
- Pterostilbene Supplements LowPeople reports
- Pygeum africanum (Bark) Supplements MediumPeople reports
- Quercetin Supplements LowPeople reports
- Red Clover Supplements LowPeople reports
- Red Yeast Rice Supplements LowPeople reports
- Resveratrol Supplements LowClinical
- Rosemary Extract Supplements LowPeople reports
- Rutin Supplements LowPeople reports
- Sabroxy Supplements LowPeople reports
- Saffron Extract Supplements LowPeople reports
- SAM-e Supplements MediumClinical
- Saw Palmetto Supplements MediumClinical
- Schisandra Supplements MediumPeople reports
- Selenium Supplements LowTheoretical
- Serine Supplements LowPeople reports
- Shiitake Supplements LowPeople reports
- Shilajit Supplements MediumPeople reports
- Silica Supplements LowPeople reports
- Spermidine Supplements LowPeople reports
- Spirulina Supplements MediumPeople reports
- St. John's Wort Supplements MediumClinical
- Sulbutiamine Supplements LowPeople reports
- Sulforaphane Supplements MediumClinical
- Sunifiram Supplements LowPeople reports
- Superoxide Dismutase (SOD) Supplements LowPeople reports
- Tadalafil (Cialis) Supplements LowClinical
- Taurine Supplements LowPeople reports
- Tauroursodeoxycholic acid (TUDCA) Supplements MediumPeople reports
- Theobromine Supplements LowPeople reports
- Tongkat Ali Supplements LowPeople reports
- Tribulus Terrestris Supplements LowPeople reports
- Trypsin Supplements MediumClinical
- Tryptophan Supplements MediumPeople reports
- Tyrosine Supplements LowPeople reports
- Uridine Supplements LowPeople reports
- Valerian Root Supplements LowClinical
- Vinpocetine Supplements LowPeople reports
- Vitamin B2 Supplements LowPeople reports
- Vitamin B3 Supplements LowPeople reports
- Vitamin B6 Supplements LowPeople reports
- Vitamin B7 Supplements LowPeople reports
- Vitamin C Supplements MediumClinical
- Vitamin E Supplements LowClinical
- Vitamin K1 Supplements LowPeople reports
- Yohimbine Supplements LowPeople reports
- Zinc Supplements MediumClinical
- 5Rhythms Dance Practices MediumPeople reports
- Alternate Day Fasting Practices MediumPeople reports
- Animal Flow Practices LowPeople reports
- Ashtanga Yoga Practices LowPeople reports
- Ayurveda Practices MediumPeople reports
- Belly Dance Practices LowPeople reports
- Brisk Walking Practices LowPeople reports
- Carb Cycling Practices HighPeople reports
- Contemporary Dance Practices MediumPeople reports
- CrossFit Practices MediumPeople reports
- Cycle Syncing Practices LowPeople reports
- Cycling Practices MediumClinical
- Dance/Movement Therapy Practices LowPeople reports
- DASH Diet Practices HighPeople reports
- Elimination Diet Practices HighPeople reports
- Existential Therapy Practices LowPeople reports
- Family Therapy Practices LowPeople reports
- Fasting Mimicking Diet Practices MediumClinical
- Free / Intuitive Dance Practices LowPeople reports
- Functional Training Practices LowPeople reports
- Group Therapy Practices MediumPeople reports
- Herbalism / Phytotherapy Practices HighPeople reports
- High-Intensity Interval Training (HIIT) Practices LowPeople reports
- High-Fiber and Vegetable Diet Practices HighClinical
- Iyengar Yoga Practices LowPeople reports
- Jnana Yoga Practices LowPeople reports
- Running / Jogging Practices MediumClinical
- Juice Fasting Practices HighPeople reports
- Kettlebell Training Practices LowPeople reports
- Kriya Yoga Practices LowPeople reports
- Kundalini Yoga Practices LowPeople reports
- Low FODMAP Diet Practices LowPeople reports
- Lunar Cycle Syncing Practices LowPeople reports
- Naturopathy Practices HighPeople reports
- Nutrition Tracking Practices LowPeople reports
- Plant-Based Diet Practices HighClinical
- Portion Control Practices MediumClinical
- Prenatal Yoga Practices HighClinical
- Reflexology Practices MediumPeople reports
- Restorative Yoga Practices LowPeople reports
- Indoor Rowing Practices MediumClinical
- Sivananda Yoga Practices LowPeople reports
- Strength Training Practices LowClinical
- Swedish Massage Practices LowPeople reports
- Trail Running Practices HighPeople reports
- Time-Restricted Eating 14/10 Practices MediumPeople reports
- Vinyasa Yoga Practices LowPeople reports
- Prolonged Water Fasting Practices LowPeople reports
- Zumba Practices LowPeople reports
- Adequate Protein Intake Habits MediumPeople reports
- Avoid Sugar Habits LowPeople reports
- Binge Eating Episodes Habits Very highClinical
- Binge-Watching TV Shows for Hours Habits MediumPeople reports
- Blaming Others for Personal Problems Habits MediumClinical
- Suppressing Emotions Habits Very highClinical
- Breathwork Habits LowPeople reports
- Cardiovascular Exercise Habits LowClinical
- Catastrophizing (Assuming the Worst) Habits MediumClinical
- Compulsive Online Shopping Habits MediumClinical
- Consume Healthy Fats Habits MediumPeople reports
- Consume Probiotics Habits HighClinical
- People-Pleasing to Your Own Detriment Habits MediumClinical
- Doomscrolling (Consuming Negative News) Habits MediumClinical
- Drug Use Habits HighPeople reports
- Eat Whole Foods Habits HighClinical
- Eating Too Quickly Habits HighClinical
- Avoiding Difficult Emotions Habits MediumTheoretical
- Emotional Eating Habits Very highPeople reports
- Energy Drink Consumption Habits MediumPeople reports
- Engaging in Conflict Habits MediumClinical
- Engaging in Negative Gossip Habits MediumClinical
- Excessive Caffeine Intake Habits HighClinical
- Excessive Video Gaming Habits LowPeople reports
- Excessive Sugar Consumption Habits HighPeople reports
- Fast Food Consumption Habits HighPeople reports
- High-Fiber Diet Habits Very highTheoretical
- High Saturated and Trans Fat Intake Habits MediumClinical
- Intermittent Fasting Habits MediumPeople reports
- Irregular Sleep-Wake Schedule Habits LowClinical
- Caffeine Consumption Late in the Day Habits MediumClinical
- Eating Large Meals Late at Night Habits HighClinical
- Maladaptive Perfectionism Habits Very highClinical
- Mindless Snacking Habits MediumPeople reports
- Engaging in Negative Self-Talk Habits HighTheoretical
- Not eating enough Habits HighPeople reports
- Plant Intake Habits MediumClinical
- Maintaining Poor Posture Habits MediumClinical
- Eating Highly Processed Foods Habits HighPeople reports
- Chronic Procrastination Habits MediumClinical
- Reckless Driving Habits MediumClinical
- Recreational Sports Habits LowPeople reports
- Engaging in Self-Sabotaging Behaviors Habits HighClinical
- Poor Financial Management Habits MediumClinical
- Unrealistic Expectations of Self Habits MediumClinical
- Evening Wind-Down Routine Habits LowClinical
- Yoga Practice Habits LowPeople reports