Effects · psyche adverse
Irritability
Increased excitability, tendency towards negative emotional reactions (anger, dissatisfaction) to minor stimuli, reduced tolerance. Can interfere with social interaction.
- Supplements
- 48
- Practices
- 52
- Habits
- 69
How we rate evidence
Probability — how likely the effect is to show up
- Very high
- High
- Medium
- Low
Evidence — where the data comes from
- Scientific Meta-analyses and randomized trials
- Clinical Clinical trials and practice
- Animal research Animal studies
- People reports User reports and anecdotes
- Theoretical Mechanistic reasoning, not yet tested
Reported as a side effect of (169)
Probability Very high 8 High 26 Medium 50 Low 85
Evidence Clinical 59 People reports 106 Theoretical 4
- Adrafinil Supplements MediumClinical
- Alpha-GPC Supplements LowPeople reports
- Amanita Regalis Supplements LowPeople reports
- Anastrozole Supplements LowTheoretical
- Ashwagandha Supplements LowPeople reports
- D-Aspartic Acid Supplements LowPeople reports
- BPC-157 Supplements LowPeople reports
- Bromantane Supplements MediumPeople reports
- Caffeine Supplements MediumPeople reports
- Clomiphene Supplements LowPeople reports
- Coluracetam Supplements LowPeople reports
- DHEA Supplements LowPeople reports
- Dihexa Supplements LowPeople reports
- Diindolylmethane (DIM) Supplements LowPeople reports
- DMAE Supplements LowPeople reports
- Eleuthero Supplements LowPeople reports
- Ethanol (alcohol) Supplements MediumPeople reports
- Fadogia Agrestis Supplements LowPeople reports
- Fasoracetam Supplements LowPeople reports
- Guarana Supplements LowPeople reports
- Horny Goat Weed Supplements LowPeople reports
- IDRA-21 Supplements LowPeople reports
- Melatonin Supplements LowPeople reports
- Modafinil Supplements LowPeople reports
- Mucuna Pruriens (Velvet Bean) Supplements LowPeople reports
- N-Acetyl-L-Tyrosine (NALT) Supplements LowPeople reports
- Nicotine Supplements LowPeople reports
- Noopept Supplements LowPeople reports
- NSI-189 Supplements LowPeople reports
- Oxiracetam Supplements MediumPeople reports
- Panax Ginseng Supplements LowPeople reports
- Phenibut Supplements LowPeople reports
- Phenylalanine Supplements LowPeople reports
- Phenylpiracetam (Phenotropil) Supplements MediumPeople reports
- Piracetam Supplements LowPeople reports
- Pregnenolone Supplements LowPeople reports
- Rhodiola Rosea Supplements LowPeople reports
- Selank Supplements LowPeople reports
- Serine Supplements LowPeople reports
- Sulbutiamine Supplements LowPeople reports
- Sunifiram Supplements LowPeople reports
- Tongkat Ali Supplements LowPeople reports
- Tyrosine Supplements LowPeople reports
- Unifiram Supplements MediumPeople reports
- Uridine Supplements LowPeople reports
- Vitamin B9 Supplements LowPeople reports
- Yohimbine Supplements MediumPeople reports
- Zinc Supplements LowPeople reports
- 5Rhythms Dance Practices LowPeople reports
- Acceptance and Commitment Therapy Practices LowPeople reports
- Alternate Day Fasting Practices HighClinical
- Art Journaling / Sketching Practices LowPeople reports
- Professional Art Therapy Practices LowPeople reports
- Ashtanga Yoga Practices LowPeople reports
- Avoiding Heavy Meals Before Bed Practices LowPeople reports
- Cognitive Training / Brain Games Practices MediumPeople reports
- Carb Cycling Practices MediumPeople reports
- Cognitive Behavioral Therapy Practices LowClinical
- Consistent Sleep Schedule Practices LowClinical
- Contemporary Dance Practices LowPeople reports
- Couples Therapy Practices MediumClinical
- Dance/Movement Therapy Practices LowClinical
- Dawn Simulation Alarm Clock Practices LowPeople reports
- Dialectical Behavior Therapy Practices MediumClinical
- Digital Art Creation Practices LowPeople reports
- EEG Neurofeedback Practices LowClinical
- Elimination Diet Practices HighPeople reports
- Expressive Writing Practices LowPeople reports
- Fasting Mimicking Diet Practices HighClinical
- Focused Attention Meditation Practices LowPeople reports
- Detailed Food Diary Practices MediumPeople reports
- Group Therapy Practices MediumPeople reports
- Guided Imagery Practices LowPeople reports
- Hiking Practices LowPeople reports
- Holotropic Breathwork Practices LowPeople reports
- Intermittent Calorie Restriction Practices MediumClinical
- Interpersonal Therapy Practices LowClinical
- Isochronic Tones Practices LowPeople reports
- Running / Jogging Practices LowPeople reports
- Juice Fasting Practices HighPeople reports
- Ketogenic Diet Practices MediumPeople reports
- Kriya Yoga Practices LowPeople reports
- Kundalini Yoga Practices LowPeople reports
- Low FODMAP Diet Practices LowPeople reports
- Professional Music Therapy Practices LowPeople reports
- Periodic 24-hour Fasting Practices MediumPeople reports
- Portion Control Practices LowClinical
- Power Nap Practices MediumPeople reports
- Psychodynamic Therapy Practices LowPeople reports
- Raja Yoga Practices LowPeople reports
- Reducing Sugar and Processed Foods Practices MediumClinical
- Sleep Tracking Practices LowPeople reports
- Strength Training Practices LowClinical
- Thai Massage Practices LowPeople reports
- Trail Running Practices LowClinical
- Time-Restricted Eating 14/10 Practices MediumPeople reports
- Time-Restricted Eating 16/8 Practices HighPeople reports
- Vipassana Meditation Practices MediumPeople reports
- Prolonged Water Fasting Practices MediumPeople reports
- Zazen Meditation Practices LowClinical
- Alcohol Consumption Habits MediumClinical
- All-or-Nothing (Black and White) Thinking Habits LowClinical
- Avoid Processed Foods Habits LowPeople reports
- Avoid Sugar Habits MediumPeople reports
- Binge Eating Episodes Habits MediumPeople reports
- Binge-Watching TV Shows for Hours Habits MediumClinical
- Blaming Others for Personal Problems Habits HighClinical
- Suppressing Emotions Habits HighClinical
- Brain Training Habits LowPeople reports
- Breathwork Habits LowPeople reports
- Cardiovascular Exercise Habits LowClinical
- Catastrophizing (Assuming the Worst) Habits MediumClinical
- Chronic Complaining Habits HighClinical
- Cigarette Smoking Habits Very highClinical
- Compulsive Online Shopping Habits Very highClinical
- Compulsively Checking Phone Notifications Habits MediumPeople reports
- Consistent Sleep Schedule Habits Very highTheoretical
- People-Pleasing to Your Own Detriment Habits Very highClinical
- Digital Detox Habits HighClinical
- Doomscrolling (Consuming Negative News) Habits HighClinical
- Drug Use Habits Very highClinical
- Avoiding Difficult Emotions Habits MediumClinical
- Emotional Eating Habits LowPeople reports
- Energy Drink Consumption Habits MediumClinical
- Engaging in Conflict Habits HighClinical
- Engaging in Negative Gossip Habits MediumClinical
- Excessive Caffeine Intake Habits HighClinical
- Excessive Video Gaming Habits MediumClinical
- Excessive Pornography Consumption Habits HighPeople reports
- Excessive Social Media Use Habits MediumPeople reports
- Excessive Sugar Consumption Habits MediumClinical
- Excessive Worrying Habits HighClinical
- Fast Food Consumption Habits LowPeople reports
- Napping Too Long or Late in the Day Habits MediumPeople reports
- Inhalant Abuse Habits HighPeople reports
- Insufficient Sleep Habits Very highClinical
- Intermittent Fasting Habits MediumPeople reports
- Irregular Sleep-Wake Schedule Habits HighTheoretical
- Caffeine Consumption Late in the Day Habits MediumClinical
- Learn New Things Habits MediumPeople reports
- Insufficient Fruit and Vegetable Intake Habits MediumTheoretical
- Maladaptive Perfectionism Habits HighClinical
- Manage Calorie Intake Habits MediumPeople reports
- Meditation Habits LowPeople reports
- Mindless Scrolling on Devices Habits MediumPeople reports
- Morning Exercise Habits LowClinical
- Music Practice Habits MediumPeople reports
- Engaging in Negative Self-Talk Habits HighClinical
- Not eating enough Habits HighPeople reports
- Comparing Self Negatively to Others Online Habits LowPeople reports
- Chronic Oversleeping Habits LowClinical
- Maintaining Poor Posture Habits MediumClinical
- Reckless Driving Habits MediumClinical
- Revenge Bedtime Procrastination Habits HighClinical
- Ruminating on Past Mistakes Habits MediumClinical
- Using Screens in Bed Habits HighClinical
- Seeking Constant External Validation Habits MediumClinical
- Engaging in Self-Sabotaging Behaviors Habits Very highPeople reports
- Compulsive Skin Picking Habits HighClinical
- Skipping Rest Breaks During Work Habits MediumClinical
- Using Smokeless Tobacco Habits MediumClinical
- Self-Imposed Social Isolation Habits HighClinical
- Using Anabolic Steroids Habits HighClinical
- Strength Training Habits LowClinical
- Poor Financial Management Habits MediumPeople reports
- Teeth Grinding (Bruxism) Habits MediumPeople reports
- Unrealistic Expectations of Self Habits HighClinical
- Vaping or E-Cigarette Use Habits HighClinical
- Working Excessive Hours Habits Very highClinical
Mitigated by (7)
- Caffeine Supplements People reports
- Green Tea Extract Supplements People reports
- Kava Kava Supplements People reports
- Nicotine Supplements Theoretical
- Panax Ginseng Supplements People reports
- Phenibut Supplements People reports
- Unifiram Supplements People reports