Effects · psyche adverse
Increased Anxiety
Occurrence or intensification of feelings of restlessness, nervousness, tension, fear, or panic attacks during supplement intake.
- Supplements
- 71
- Practices
- 96
- Habits
- 85
How we rate evidence
Probability — how likely the effect is to show up
- Very high
- High
- Medium
- Low
Evidence — where the data comes from
- Scientific Meta-analyses and randomized trials
- Clinical Clinical trials and practice
- Animal research Animal studies
- People reports User reports and anecdotes
- Theoretical Mechanistic reasoning, not yet tested
Reported as a side effect of (252)
Probability Very high 18 High 34 Medium 45 Low 155
Evidence Clinical 92 People reports 114 Theoretical 46
- 9-Me-BC Supplements MediumPeople reports
- Adrafinil Supplements MediumClinical
- Alpha-GPC Supplements LowPeople reports
- Amanita Muscaria Supplements LowPeople reports
- Amanita Pantherina Supplements MediumPeople reports
- Amanita Regalis Supplements LowPeople reports
- Anastrozole Supplements LowTheoretical
- Aniracetam Supplements LowPeople reports
- Apigenin Supplements LowPeople reports
- Ashwagandha Supplements LowPeople reports
- Bromantane Supplements MediumPeople reports
- Caffeine Supplements MediumTheoretical
- CDP-Choline Supplements LowPeople reports
- Cerebrolysin Supplements LowClinical
- Coluracetam Supplements LowPeople reports
- Dihexa Supplements LowPeople reports
- Diindolylmethane (DIM) Supplements LowPeople reports
- DL-Phenylalanine (DLPA) Supplements LowPeople reports
- DMAE Supplements LowPeople reports
- Dutasteride Supplements LowClinical
- Eleuthero Supplements LowPeople reports
- Ethanol (alcohol) Supplements MediumTheoretical
- Fasoracetam Supplements LowPeople reports
- GABA Supplements LowPeople reports
- Ginkgo Biloba Supplements LowPeople reports
- Green Tea Extract Supplements LowPeople reports
- Guarana Supplements MediumTheoretical
- Histidine Supplements LowPeople reports
- Honokiol Supplements LowPeople reports
- Horny Goat Weed Supplements LowPeople reports
- Huperzine A Supplements LowPeople reports
- IDRA-21 Supplements LowPeople reports
- Inositol Supplements LowPeople reports
- J147 Supplements LowPeople reports
- L-Carnitine Supplements LowPeople reports
- Lion's Mane Supplements LowPeople reports
- Magnolia Bark Extract Supplements LowPeople reports
- Memantine Supplements LowPeople reports
- Methionine Supplements LowClinical
- Methylene Blue Supplements MediumPeople reports
- Modafinil Supplements LowTheoretical
- Mucuna Pruriens (Velvet Bean) Supplements LowPeople reports
- N-Acetyl-L-Tyrosine (NALT) Supplements LowPeople reports
- Noopept Supplements LowPeople reports
- NSI-189 Supplements LowPeople reports
- Oxiracetam Supplements LowPeople reports
- Phenylalanine Supplements LowPeople reports
- Phenylpiracetam (Phenotropil) Supplements MediumPeople reports
- Picamilon Supplements LowPeople reports
- Piracetam Supplements LowPeople reports
- PQQ Supplements LowPeople reports
- Pramiracetam Supplements LowPeople reports
- Pregnenolone Supplements MediumPeople reports
- PRL-8-53 Supplements LowPeople reports
- Rhodiola Rosea Supplements LowPeople reports
- SAM-e Supplements LowClinical
- Schisandra Supplements LowPeople reports
- Selank Supplements LowPeople reports
- Semax Supplements LowPeople reports
- Serine Supplements LowPeople reports
- Shilajit Supplements LowPeople reports
- St. John's Wort Supplements LowClinical
- Sulbutiamine Supplements LowPeople reports
- Sunifiram Supplements LowPeople reports
- Theobromine Supplements LowPeople reports
- Tyrosine Supplements LowPeople reports
- Unifiram Supplements LowPeople reports
- Valerian Root Supplements LowPeople reports
- Vitamin B1 Supplements LowPeople reports
- Vitamin B9 Supplements LowPeople reports
- Yohimbine Supplements HighTheoretical
- 5Rhythms Dance Practices LowPeople reports
- Acceptance and Commitment Therapy Practices MediumTheoretical
- Active Music Making Practices LowClinical
- Acupuncture Practices LowPeople reports
- Alternate Day Fasting Practices LowPeople reports
- Alternate Nostril Breathing Practices LowClinical
- Art Journaling / Sketching Practices LowPeople reports
- Professional Art Therapy Practices MediumClinical
- Ashtanga Yoga Practices LowPeople reports
- Bhakti Yoga Practices LowClinical
- Bhastrika Pranayama Practices LowClinical
- Binaural Beats Practices LowPeople reports
- Body Scan Meditation Practices LowClinical
- Box Breathing Practices LowClinical
- Cognitive Training / Brain Games Practices MediumPeople reports
- Buteyko Method Breathing Practices LowPeople reports
- Cognitive Behavioral Therapy Practices MediumTheoretical
- Coherent Breathing Practices LowClinical
- Cold Shower Practices LowPeople reports
- Cold Water Face Plunge Practices LowClinical
- Contemporary Dance Practices LowPeople reports
- Contrast Shower Practices MediumTheoretical
- Couples Therapy Practices HighTheoretical
- CrossFit Practices LowPeople reports
- Cryotherapy Chamber / Whole Body Cryotherapy Practices LowPeople reports
- Cycle Syncing Practices LowPeople reports
- Dance/Movement Therapy Practices MediumClinical
- Dawn Simulation Alarm Clock Practices LowPeople reports
- Dialectical Behavior Therapy Practices HighClinical
- Diaphragmatic Breathing Practices LowClinical
- Digital Art Creation Practices MediumPeople reports
- Ecstatic Dance Practices LowPeople reports
- EEG Neurofeedback Practices LowClinical
- Elimination Diet Practices MediumPeople reports
- Eye Movement Desensitization and Reprocessing Practices HighTheoretical
- Energizing Music Listening Practices LowPeople reports
- Existential Therapy Practices HighClinical
- Expressive Writing Practices HighClinical
- Family Therapy Practices HighClinical
- Fasting Mimicking Diet Practices LowClinical
- Focused Attention Meditation Practices LowClinical
- Detailed Food Diary Practices HighTheoretical
- Goal Setting Journal Practices LowClinical
- Group Therapy Practices HighClinical
- Guided Imagery Practices LowClinical
- Habit Tracking Journal Practices LowClinical
- Hatha Yoga Practices LowPeople reports
- Herbalism / Phytotherapy Practices LowPeople reports
- Holotropic Breathwork Practices MediumClinical
- Hot Stone Massage Practices LowPeople reports
- Humanistic Therapy Practices MediumClinical
- Ice Bath / Cold Plunge Practices HighClinical
- Intermittent Calorie Restriction Practices MediumClinical
- Interpersonal Therapy Practices MediumClinical
- Isochronic Tones Practices MediumPeople reports
- Juice Fasting Practices MediumPeople reports
- Kriya Yoga Practices LowClinical
- Kundalini Yoga Practices LowPeople reports
- Low FODMAP Diet Practices LowClinical
- Mantra Meditation Practices LowPeople reports
- Mindfulness Meditation Practices LowClinical
- Morning Bright Light / Sunlight Exposure Practices LowClinical
- Professional Music Therapy Practices LowClinical
- Nature Sounds Listening Practices LowPeople reports
- Naturopathy Practices LowPeople reports
- Nutrition Tracking Practices LowClinical
- Open Monitoring Meditation Practices LowClinical
- Psychodynamic Therapy Practices HighClinical
- Raja Yoga Practices LowClinical
- Rebirthing Breathwork Practices HighClinical
- Reducing Sugar and Processed Foods Practices LowPeople reports
- Restorative Yoga Practices LowClinical
- SAD Lamp Light Therapy Practices LowClinical
- Singing Bowls Session Practices LowPeople reports
- Sivananda Yoga Practices LowPeople reports
- Sleep Tracking Practices MediumClinical
- White / Pink Noise for Sleep Practices LowPeople reports
- Sound Meditation Practices LowPeople reports
- Steam Room / Hammam Practices LowPeople reports
- Strength Training Practices LowClinical
- Swedish Massage Practices LowPeople reports
- Cycle Symptom Logging Practices LowClinical
- Tantra Yoga Practices LowPeople reports
- Thai Massage Practices LowPeople reports
- Trail Running Practices LowClinical
- Transcendental Meditation Practices LowClinical
- Time-Restricted Eating 14/10 Practices LowPeople reports
- Time-Restricted Eating 16/8 Practices MediumPeople reports
- Values Clarification Journal Practices LowClinical
- Vipassana Meditation Practices HighClinical
- Visualization Meditation Practices LowClinical
- Prolonged Water Fasting Practices MediumPeople reports
- Wearable ECG Monitoring Practices LowClinical
- Weighted Blanket Practices LowPeople reports
- Wim Hof Method Breathing Practices LowPeople reports
- Zazen Meditation Practices LowClinical
- Using Alcohol as a Sleep Aid Habits MediumClinical
- Alcohol Consumption Habits MediumClinical
- All-or-Nothing (Black and White) Thinking Habits HighTheoretical
- Avoid Sugar Habits MediumPeople reports
- Binge Eating Episodes Habits Very highClinical
- Binge-Watching TV Shows for Hours Habits MediumClinical
- Blaming Others for Personal Problems Habits HighClinical
- Suppressing Emotions Habits Very highTheoretical
- Brain Training Habits LowPeople reports
- Breathwork Habits LowClinical
- Bulimia Habits Very highTheoretical
- Cardiovascular Exercise Habits LowPeople reports
- Catastrophizing (Assuming the Worst) Habits Very highTheoretical
- Chronic Complaining Habits HighTheoretical
- Cigarette Smoking Habits HighTheoretical
- Cold Exposure Habits LowClinical
- Compulsive Online Shopping Habits Very highTheoretical
- Compulsively Checking Phone Notifications Habits Very highTheoretical
- Consistent Sleep Schedule Habits Very highTheoretical
- Creative Expression Habits LowPeople reports
- People-Pleasing to Your Own Detriment Habits Very highTheoretical
- Digital Detox Habits HighClinical
- Doomscrolling (Consuming Negative News) Habits Very highTheoretical
- Drug Use Habits Very highTheoretical
- Avoiding Difficult Emotions Habits HighTheoretical
- Emotional Eating Habits MediumClinical
- Energy Drink Consumption Habits HighClinical
- Engaging in Conflict Habits Very highTheoretical
- Engaging in Negative Gossip Habits HighClinical
- Excessive Video Gaming Habits MediumClinical
- Excessive Pornography Consumption Habits MediumClinical
- Excessive Social Media Use Habits HighTheoretical
- Excessive Sugar Consumption Habits MediumClinical
- Fast Food Consumption Habits LowClinical
- Heat Exposure (Sauna/Steam) Habits LowPeople reports
- Inhalant Abuse Habits HighPeople reports
- Insufficient Sleep Habits HighTheoretical
- Intermittent Fasting Habits MediumPeople reports
- Irregular Sleep-Wake Schedule Habits MediumTheoretical
- Caffeine Consumption Late in the Day Habits MediumClinical
- Learn New Things Habits LowPeople reports
- Limit News Consumption Habits LowPeople reports
- Maladaptive Perfectionism Habits Very highTheoretical
- Manage Calorie Intake Habits LowPeople reports
- Meaningful Social Connection Habits LowClinical
- Meditation Habits LowTheoretical
- Mindless Scrolling on Devices Habits HighTheoretical
- Monitor Blood Glucose Habits MediumTheoretical
- Monitor Blood Pressure Habits MediumTheoretical
- Morning Exercise Habits LowClinical
- Mouth Taping for Sleep Habits LowClinical
- Music Practice Habits MediumClinical
- Nail Biting Habits MediumClinical
- Engaging in Negative Self-Talk Habits Very highTheoretical
- Comparing Self Negatively to Others Online Habits HighTheoretical
- Over-the-Counter Drug Abuse Habits HighClinical
- Maintaining Poor Posture Habits LowClinical
- Practice Mindfulness Habits LowClinical
- Eating Highly Processed Foods Habits LowTheoretical
- Chronic Procrastination Habits HighTheoretical
- Prolonged Sitting Habits HighTheoretical
- Reckless Driving Habits HighClinical
- Recreational Sports Habits LowPeople reports
- Revenge Bedtime Procrastination Habits LowClinical
- Ruminating on Past Mistakes Habits HighTheoretical
- Using Screens in Bed Habits HighClinical
- Seeking Constant External Validation Habits Very highTheoretical
- Engaging in Self-Sabotaging Behaviors Habits Very highTheoretical
- Self Skin Examination Habits LowClinical
- Compulsive Skin Picking Habits Very highTheoretical
- Skipping Rest Breaks During Work Habits LowClinical
- Using a Sleep Mask Habits LowPeople reports
- Using Smokeless Tobacco Habits MediumClinical
- Self-Imposed Social Isolation Habits Very highTheoretical
- Using Anabolic Steroids Habits MediumClinical
- Strength Training Habits LowClinical
- Poor Financial Management Habits Very highTheoretical
- Teeth Grinding (Bruxism) Habits MediumClinical
- Track Body Composition Habits LowClinical
- Unrealistic Expectations of Self Habits HighTheoretical
- Using BioMaxing Life App Habits LowPeople reports
- Vagus Nerve Stimulation Habits LowPeople reports
- Vaping or E-Cigarette Use Habits HighClinical
- Evening Wind-Down Routine Habits LowClinical
- Yoga Practice Habits LowClinical
Mitigated by (25)
- 5-HTP Supplements People reports
- 9-Me-BC Supplements People reports
- Amanita Pantherina Supplements People reports
- Amanita Regalis Supplements People reports
- Ashwagandha Supplements People reports
- Ethanol (alcohol) Supplements Theoretical
- Fasoracetam Supplements People reports
- GABA Supplements People reports
- Honokiol Supplements People reports
- IDRA-21 Supplements People reports
- Jujube Seed Extract Supplements People reports
- Kava Kava Supplements People reports
- Magnolia Bark Extract Supplements People reports
- Memantine Supplements People reports
- Nicotine Supplements Theoretical
- NSI-189 Supplements People reports
- Passionflower Supplements People reports
- Phenibut Supplements Clinical
- Picamilon Supplements People reports
- Propranolol Supplements Clinical
- Selank Supplements People reports
- St. John's Wort Supplements People reports
- Tryptophan Supplements People reports
- Unifiram Supplements People reports
- Valerian Root Supplements People reports