Effects · psyche adverse
Mental Fatigue
Feeling of exhaustion of mental resources, difficulty concentrating, remembering, making decisions, decreased mental clarity, occurring as an undesirable effect.
- Supplements
- 20
- Practices
- 72
- Habits
- 60
How we rate evidence
Probability — how likely the effect is to show up
- Very high
- High
- Medium
- Low
Evidence — where the data comes from
- Scientific Meta-analyses and randomized trials
- Clinical Clinical trials and practice
- Animal research Animal studies
- People reports User reports and anecdotes
- Theoretical Mechanistic reasoning, not yet tested
Reported as a side effect of (152)
Probability Very high 13 High 44 Medium 39 Low 56
Evidence Clinical 56 People reports 85 Theoretical 11
- Alpha-GPC Supplements LowPeople reports
- Amanita Regalis Supplements LowPeople reports
- Anastrozole Supplements MediumTheoretical
- Apigenin Supplements LowPeople reports
- Ashwagandha Supplements LowPeople reports
- Bacopa Monnieri Supplements LowPeople reports
- Cabergoline Supplements MediumPeople reports
- Cerebrolysin Supplements LowPeople reports
- Chlorella Supplements LowPeople reports
- Dutasteride Supplements LowPeople reports
- Ethanol (alcohol) Supplements HighTheoretical
- Kava Kava Supplements LowPeople reports
- Melatonin Supplements MediumPeople reports
- Memantine Supplements LowPeople reports
- Oxiracetam Supplements LowPeople reports
- Phenibut Supplements MediumPeople reports
- Serine Supplements LowPeople reports
- St. John's Wort Supplements LowPeople reports
- Unifiram Supplements LowPeople reports
- Uridine Supplements LowPeople reports
- 5Rhythms Dance Practices LowPeople reports
- Acceptance and Commitment Therapy Practices MediumPeople reports
- Active Music Making Practices MediumClinical
- Alternate Day Fasting Practices HighClinical
- Animal Flow Practices LowPeople reports
- Art Journaling / Sketching Practices LowPeople reports
- Professional Art Therapy Practices MediumClinical
- Ashtanga Yoga Practices LowPeople reports
- Ayurveda Practices LowPeople reports
- Balance Training Practices LowPeople reports
- Ballet Fitness Practices LowPeople reports
- Bhakti Yoga Practices LowClinical
- Cognitive Training / Brain Games Practices HighClinical
- Bullet Journal Practices LowPeople reports
- Calisthenics Practices HighPeople reports
- Cognitive Behavioral Therapy Practices MediumClinical
- Clay Sculpting / Modeling Practices HighPeople reports
- Contemporary Dance Practices MediumPeople reports
- Couples Therapy Practices HighClinical
- CrossFit Practices MediumPeople reports
- Dance/Movement Therapy Practices MediumClinical
- Dialectical Behavior Therapy Practices HighPeople reports
- Digital Art Creation Practices HighPeople reports
- Ecstatic Dance Practices LowPeople reports
- EEG Neurofeedback Practices MediumClinical
- Eye Movement Desensitization and Reprocessing Practices HighTheoretical
- Existential Therapy Practices HighClinical
- Expressive Writing Practices HighPeople reports
- Family Therapy Practices HighPeople reports
- Detailed Food Diary Practices HighPeople reports
- Group Therapy Practices HighPeople reports
- Guided Imagery Practices LowPeople reports
- Hiking Practices MediumClinical
- Holotropic Breathwork Practices Very highClinical
- HRV Biofeedback Training Practices LowClinical
- Humanistic Therapy Practices MediumClinical
- Integral Yoga Practices LowPeople reports
- Interpersonal Therapy Practices LowClinical
- Intuitive Painting / Drawing Practices LowPeople reports
- Isochronic Tones Practices LowPeople reports
- Iyengar Yoga Practices LowPeople reports
- Jivamukti Yoga Practices MediumClinical
- Jnana Yoga Practices LowPeople reports
- Running / Jogging Practices MediumClinical
- Kettlebell Training Practices LowPeople reports
- Kundalini Yoga Practices LowPeople reports
- Lunar Cycle Syncing Practices LowTheoretical
- Mandala Coloring / Anti-Stress Coloring Practices MediumPeople reports
- Mindful Photography Practices LowClinical
- Professional Music Therapy Practices MediumClinical
- Manual Myofascial Release Practices MediumPeople reports
- Nature Sounds Listening Practices LowPeople reports
- Naturopathy Practices MediumPeople reports
- Negative Thought Record Practices MediumClinical
- Nutrition Tracking Practices LowPeople reports
- Origami Practices MediumPeople reports
- Psychodynamic Therapy Practices HighPeople reports
- Raja Yoga Practices LowPeople reports
- Indoor Rowing Practices LowClinical
- Scrapbooking Practices MediumPeople reports
- Singing Bowls Session Practices LowPeople reports
- Sleep Tracking Practices LowPeople reports
- Strength Training Practices LowClinical
- Thai Massage Practices LowPeople reports
- Trail Running Practices HighPeople reports
- Transcendental Meditation Practices LowPeople reports
- Time-Restricted Eating 14/10 Practices MediumPeople reports
- Values Clarification Journal Practices MediumClinical
- Vipassana Meditation Practices HighPeople reports
- Visualization Meditation Practices LowPeople reports
- Prolonged Water Fasting Practices Very highPeople reports
- Zazen Meditation Practices MediumPeople reports
- Alcohol Consumption Habits HighTheoretical
- All-or-Nothing (Black and White) Thinking Habits MediumClinical
- Avoid Sugar Habits HighPeople reports
- Balance Training Habits LowClinical
- Binge Eating Episodes Habits HighClinical
- Binge-Watching TV Shows for Hours Habits HighClinical
- Blaming Others for Personal Problems Habits MediumClinical
- Suppressing Emotions Habits Very highTheoretical
- Brain Training Habits MediumClinical
- Breathwork Habits LowPeople reports
- Cardiovascular Exercise Habits LowClinical
- Catastrophizing (Assuming the Worst) Habits HighClinical
- Chronic Complaining Habits MediumClinical
- Cigarette Smoking Habits HighClinical
- Compulsive Online Shopping Habits HighClinical
- Compulsively Checking Phone Notifications Habits HighPeople reports
- Consistent Sleep Schedule Habits Very highTheoretical
- Creative Expression Habits HighTheoretical
- People-Pleasing to Your Own Detriment Habits Very highClinical
- Digital Detox Habits MediumPeople reports
- Avoiding Difficult Emotions Habits HighPeople reports
- Emotional Eating Habits MediumPeople reports
- Energy Drink Consumption Habits HighClinical
- Engaging in Conflict Habits Very highClinical
- Engaging in Negative Gossip Habits MediumClinical
- Excessive Caffeine Intake Habits HighClinical
- Excessive Video Gaming Habits HighClinical
- Excessive Social Media Use Habits HighPeople reports
- Excessive Worrying Habits Very highTheoretical
- Fast Food Consumption Habits MediumPeople reports
- Inactive Lifestyle Habits MediumClinical
- Intermittent Fasting Habits MediumPeople reports
- Learn New Things Habits HighClinical
- Insufficient Fruit and Vegetable Intake Habits HighClinical
- Maladaptive Perfectionism Habits Very highClinical
- Manage Calorie Intake Habits MediumPeople reports
- Meaningful Social Connection Habits LowPeople reports
- Meditation Habits LowPeople reports
- Monitor Blood Glucose Habits MediumClinical
- Music Practice Habits HighPeople reports
- Engaging in Negative Self-Talk Habits HighClinical
- Not eating enough Habits HighClinical
- Comparing Self Negatively to Others Online Habits MediumClinical
- Practice Mindfulness Habits LowPeople reports
- Chronic Procrastination Habits HighClinical
- Prolonged Sitting Habits HighPeople reports
- Reading Habits HighClinical
- Reckless Driving Habits LowClinical
- Revenge Bedtime Procrastination Habits Very highTheoretical
- Ruminating on Past Mistakes Habits HighPeople reports
- Using Screens in Bed Habits Very highClinical
- Seeking Constant External Validation Habits HighClinical
- Engaging in Self-Sabotaging Behaviors Habits Very highPeople reports
- Compulsive Skin Picking Habits HighPeople reports
- Skipping Rest Breaks During Work Habits Very highTheoretical
- Self-Imposed Social Isolation Habits HighClinical
- Strength Training Habits LowClinical
- Poor Financial Management Habits HighPeople reports
- Unrealistic Expectations of Self Habits Very highClinical
- Using BioMaxing Life App Habits LowPeople reports
Mitigated by (27)
- 9-Me-BC Supplements People reports
- Adrafinil Supplements People reports
- Bromantane Supplements People reports
- Caffeine Supplements Theoretical
- Coluracetam Supplements People reports
- DHEA Supplements People reports
- Dihexa Supplements People reports
- Dutasteride Supplements People reports
- Fasoracetam Supplements People reports
- Guarana Supplements Theoretical
- Huperzine A Supplements People reports
- IDRA-21 Supplements People reports
- Mucuna Pruriens (Velvet Bean) Supplements People reports
- Nicotine Supplements Theoretical
- Oxiracetam Supplements People reports
- Panax Ginseng Supplements People reports
- Phenylpiracetam (Phenotropil) Supplements People reports
- PQQ Supplements People reports
- Pregnenolone Supplements People reports
- Selegiline Supplements People reports
- Semax Supplements People reports
- Sulbutiamine Supplements People reports
- Sunifiram Supplements People reports
- Theobromine Supplements People reports
- Unifiram Supplements People reports
- Vitamin B1 Supplements People reports
- Yohimbine Supplements People reports