Effects · body
Hair Pigmentation Support
Maintenance or restoration of natural hair color, slowing down the graying process. May be related to supporting the function of melanocytes (cells producing melanin pigment) in hair follicles.
- Supplements
- 3
Start here
Highest probability, strongest evidence
- CopperSupplementsMediumClinicalNecessary for tyrosinase, an enzyme involved in melanin production, copper supports natural hair pigmentation and may help slow down premature graying, though individual results vary.
- CatalaseSupplementsLowClinicalTopical catalase aims to break down hydrogen peroxide buildup in hair follicles, which is implicated in the graying process. While theoretically sound, real-world results for restoring natural hair color can be mixed and often subtle.
- PhenylalanineSupplementsLowClinicalPhenylalanine is a precursor to melanin, the pigment responsible for hair color. While studied for conditions like vitiligo, its broader effect on natural hair pigmentation or preventing graying in healthy individuals is observed in limited cases and over extended periods.
How we rate evidence
Probability — how likely the effect is to show up
- Very high
- High
- Medium
- Low
Evidence — where the data comes from
- Scientific Meta-analyses and randomized trials
- Clinical Clinical trials and practice
- Animal research Animal studies
- People reports User reports and anecdotes
- Theoretical Mechanistic reasoning, not yet tested
Increased by
Probability Medium 1 Low 2
Evidence Clinical 3
Medium probability (1)
- Copper Supplements Clinical
Low probability (2)
- Catalase Supplements Clinical
- Phenylalanine Supplements Clinical