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Trimethylaminuria

A rare metabolic disorder where the body cannot break down trimethylamine, leading to a fishy body odor. Choline is a precursor to trimethylamine, so choline supplementation is contraindicated as it will worsen the symptoms.

What may help
1
What to avoid
11

What may help (1)

  • Elimination Diet Practices HighClinical

    For individuals with Trimethylaminuria, an elimination diet focusing on restricting choline and other trimethylamine precursors is indicated. This dietary modification significantly reduces the production of trimethylamine, effectively managing the distinctive fishy body odor associated with the condition.

What to avoid (11)

  • Betaine (TMG) Supplements HighClinical

    Do not use Betaine (TMG) if you have trimethylaminuria (fish odor syndrome), as it can significantly worsen the characteristic body odor.

  • Acetyl-L-Carnitine (ALCAR) Supplements Very highTheoretical

    Avoid if you have trimethylaminuria (fish odor syndrome), as acetyl-L-carnitine can intensify the characteristic body odor.

  • Alpha-GPC Supplements Very highTheoretical

    If you have trimethylaminuria, a condition causing a fishy body odor, avoid Alpha-GPC as it is a choline precursor and can worsen your symptoms.

  • Herbalism / Phytotherapy Practices Very highTheoretical

    Herbal remedies containing choline (e.g., lecithin-rich plants) are strictly contraindicated in trimethylaminuria, a rare metabolic disorder causing fishy body odor, as they can exacerbate symptoms. Consult a specialist.

  • L-Carnitine Supplements Very highTheoretical

    If you have trimethylaminuria (fish odor syndrome), avoid L-Carnitine as it can worsen the characteristic body odor.

  • Lecithin Supplements Very highTheoretical

    Individuals with trimethylaminuria (fish odor syndrome) should avoid phosphatidylcholine. It's a rich source of choline, which the body converts into trimethylamine, potentially worsening the characteristic body odor.

  • Phosphatidylcholine (PC) Supplements Very highTheoretical

    If you have trimethylaminuria, a rare genetic disorder causing a fishy body odor, avoid this supplement. It provides choline, which your body cannot properly break down, potentially worsening the odor.

  • CDP-Choline Supplements HighTheoretical

    If you have trimethylaminuria, a rare metabolic disorder causing a strong body odor, you should avoid CDP-Choline, as it provides choline which can worsen this condition.

  • Naturopathy Practices HighTheoretical

    Choline supplementation is strictly contraindicated as it is a precursor to trimethylamine and will worsen the characteristic fishy body odor.

  • Adequate Protein Intake Habits MediumTheoretical

    Individuals with Trimethylaminuria, a rare metabolic disorder, should limit intake of choline-rich protein sources (e.g., eggs, certain fish, offal), as choline is metabolized into trimethylamine, causing a distinct body odor.

  • Ketogenic Diet Practices LowTheoretical

    For individuals with trimethylaminuria, a rare metabolic disorder, the ketogenic diet may worsen symptoms due to the high intake of choline-rich foods, which are precursors to trimethylamine.

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